Prognostic staging for therapy of rheumatoid arthritis
Identifieur interne : 002F17 ( Main/Exploration ); précédent : 002F16; suivant : 002F18Prognostic staging for therapy of rheumatoid arthritis
Auteurs : Robert F. WillkensSource :
- Seminars in Arthritis and Rheumatism [ 0049-0172 ] ; 1991.
English descriptors
- Teeft :
- Antinuclear antibody, Arthritis, Arthritis rheum, Bone scan, Combination therapy, Drug therapy, Erythrocyte sedimentation rate, Felson, Fries, Functional improvement, Immune complexes, Joint destruction, Methotrexate, Nepom, Nonsteroidal antiinflammatory drugs, Normal hematocrit, Nsaid, Peripheral blood, Prognostic, Reactant, Rheum, Rheumatoid, Rheumatoid arthritis, Rheumatoid disease, Rheumatoid factor, Semin arthritis rheum, Steroid, Synovial, Synovial biopsy, Willkens.
Abstract
Abstract: An attempt should be made to predict the most likely course of individual disease when a patient is first diagnosed as having rheumatoid arthritis (RA). Such a prediction can be called prognostic staging for therapy. While no specific marker will accomplish this accurately, the summation of demographic, genetic, historical, physical, laboratory, radiologic, and scanning data may be used to make a reasonable estimation of outcome. The use of immunogenetic typing is the newest technique that can help identify patients likely to develop more serious disease. Once patients are identified as having probable aggressive disease, that is, beyond stage I, combination therapy should be initiated. Goals of therapy should include the prevention and/ or interference of progression of radiologic erosions, as well as functional improvement as measured by life-style and productivity.
Url:
DOI: 10.1016/0049-0172(91)90050-A
Affiliations:
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Le document en format XML
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